Short answer

A “complicated cataract” is not simply a synonym for a difficult operation. In Russian clinical usage, the term often describes lens opacity associated with another ocular or systemic disorder. Surgical complexity is broader: it is determined by the pupil, zonules, capsule, cornea, anterior chamber, posterior segment and previous procedures. Its practical value lies in defining risk, visual potential, theatre resources, a backup IOL strategy and tailored postoperative care before surgery.

Two concepts that should not be conflated

Russian-language clinical practice often uses “complicated cataract” to describe the origin of lens opacity. International literature more commonly discusses complex cataract surgery—a procedure with increased technical risk. The groups overlap, but they are not identical.

01 · diagnosis

Cataract associated with another disorder

Uveitis, trauma, glaucoma, diabetes, retinal disease and long-term corticosteroid exposure may affect both cataract formation and visual potential.

02 · procedure

Technically complex surgery

A small pupil, zonular weakness, white or brunescent cataract, shallow anterior chamber, posterior polar opacity, previous vitrectomy or absent red reflex may alter the procedure regardless of aetiology.

Practical point. A diagnostic label should not automatically determine operative difficulty, while an age-related cataract does not guarantee a routine case.

What must be established before surgery?

Preoperative assessment should answer more than “can the cataract be removed?” It should define procedural safety, attainable vision and whether the team can deliver a credible rescue strategy.

Technique

What may happen during surgery?

Anterior chamber depth, pupil size and rigidity, phacodonesis, nuclear density, capsular integrity, endothelium, corneal scars and previous procedures.

Function

What may limit the result?

Macular and optic nerve status, diabetic retinopathy, glaucomatous neuropathy, amblyopia, endothelial reserve and irregular astigmatism.

System

Can plan B actually be delivered?

Patient cooperation, anaesthetic risk, surgeon experience, access to a vitrector and alternative IOLs, and a clear vitreoretinal pathway.

ESCRS recommendations identify shallow anterior chambers, pseudoexfoliation, white and brunescent cataracts, small pupils and extreme axial length as higher-risk features. Comorbidity and risk should be discussed in advance so expectations remain realistic [ESCRS].

Which findings should change the plan?

  • shallow anterior chamber or short eye;
  • small or rigid pupil, posterior synechiae or IFIS risk;
  • pseudoexfoliation, phacodonesis or iridodonesis;
  • white, intumescent, brunescent or posterior polar cataract;
  • weak or absent red reflex.
  • uveitis, glaucoma or previous glaucoma surgery;
  • trauma or iris/zonular defects;
  • previous vitrectomy or intravitreal treatment;
  • endothelial dysfunction or corneal opacity;
  • retinal disease or limited visual potential.
Mature white cataract
Mature white cataract: loss of the red reflex and the risk of an uncontrolled anterior capsular tear alter capsulorhexis planning. Photo: Philipp Franko Zeitz, Wikimedia Commons, CC BY-SA 3.0.
Posterior polar cataract
Posterior polar cataract: its morphology warns of pre-existing weakness or a defect of the posterior capsule. Photo: Imrankabirhossain, Wikimedia Commons, CC BY-SA 4.0.

What should be prepared in the operating room?

A “complex cataract set” is useful only when each item maps to a recognised risk. Every anticipated event needs not only an instrument, but an agreed sequence of actions.

FindingLikely problemPrepareBackup strategy
Small/rigid pupilRestricted view, iris trauma, capsular tearViscodilation, iris hooks and expansion ringStepwise enlargement without excessive sphincter stress
Zonular weaknessBag decentration, dialysis, vitreous prolapseCapsular hooks, CTR, segment and fixation set when neededChange IOL fixation site/type; anterior vitrectomy if required
White cataractRunaway capsulorhexis, absent red reflexTrypan blue, cohesive OVD and decompression instrumentsControlled two-stage capsulorhexis
Shallow chamber / low endothelial reserveEndothelial contact and corneal oedemaDispersive OVD, stable fluidics and ultrasound-sparing strategyModify technique early; keratoplasty in selected eyes
Posterior capsule riskVitreous loss, dropped fragmentsVitrector, triamcinolone when indicated, alternative IOLs and suturing setAnterior vitrectomy, sulcus/optic capture or secondary fixation; vitreoretinal pathway

CTR, capsular tension ring; OVD, ophthalmic viscosurgical device. The precise strategy depends on the location and extent of zonular loss and the integrity of the capsulorhexis and posterior capsule.

How much does risk increase?

There is no single defensible number for “routine versus complicated cataract”: definitions vary and risk factors cluster. Posterior capsule rupture (PCR) rates for specific preoperative findings provide a more useful comparison.

The RCOphth NOD study included 961,208 operations from 136 centres; overall PCR was 1.01% [Sim et al., 2024].

Preoperative factorAbsent / comparisonFactor present
Brunescent, white or mature cataract0.90%2.99%
Pseudoexfoliation / phacodonesis0.98%4.84%
Glaucoma0.93%1.79%
Previous vitrectomy1.00%1.67%
Previous anti-VEGF treatment0.98%2.18%
Large / small pupil0.92%1.78%
Consultant / less-experienced trainee0.77%2.61%

Interpretation. These unadjusted rates are not causal comparisons or individual predictions, factors overlap and should not be added together.

What changes if PCR occurs?

EUREQUO included 1,371,743 operations, with PCR reported in 12,196 (0.9%). PCR was associated with worse mean vision and refractive accuracy and with more early complications [Segers et al., 2022].

OutcomeNo PCRAfter PCR
Mean postoperative CDVA0.05 logMAR0.13 logMAR
Mean absolute prediction error0.41 D1.15 D
Corneal oedema0.17%0.88%
Endophthalmitis0.02%0.11%
Uncontrolled IOP0.03%0.55%

Most eyes with PCR still improved. The table describes a shift in probability, not an inevitable poor outcome.

How should case complexity be matched to surgeon experience?

The relevant question is not whether a trainee may ever operate on a complex cataract, but what degree of independence is safe for this case?

1

Independent surgery. Risks are recognised and the surgeon is proficient in both the primary technique and the likely rescue manoeuvre.

2

A senior surgeon is present and ready to take over. The trigger and handover signal are agreed before surgery—an approach reflected in the RCOphth curriculum.

3

The case is assigned to the appropriate subspecialist from the outset. This is preferable when plan B exceeds the operator’s competence or the institution’s resources.

Experience does not mean an absence of complications. It means recognising risk before surgery, stopping at the right moment and moving to the next safe plan without delay.

The IOL and rescue technique must be planned together

When capsular support is uncertain, “a spare lens” is not enough. The sequence should be explicit: in-the-bag implantation → sulcus placement/optic capture when support is sufficient → extra-capsular fixation or delayed implantation.

From my practice. If supplementary fixation is a realistic possibility, I calculate an IOL whose design supports the intended suturing technique. Among locally available options, I use NANOoptic Citrine TT and Aquamarine TT as examples. The manufacturer describes the TT design as a two-haptic lens with manipulation holes. Current instructions for the exact model and permitted fixation routes must always be checked [manufacturer information].

Trade names describe personal practice and do not imply superiority over alternatives.

How I approach these cases

I plan both the operation and the possible deviation from it

Why does a shallow anterior chamber make surgery more difficult?

It sharply restricts working space: an otherwise ordinary instrument excursion becomes excessive, while the endothelial safety margin shrinks. Every imprecise movement and unnecessary unit of ultrasound energy therefore carries a greater corneal cost.

What should be prepared in the operating room?

I have iris hooks, a pupil expansion ring, capsular hooks and an additional set for possible IOL suturing immediately available. A vitrector and alternative IOLs are part of the plan, not a response to a problem that has already occurred.

How should expectations be set?

I explain why the operation differs from a routine case, what visual outcome is realistic, why the IOL fixation method may change and when a second procedure may be required. Setting expectations is part of safe care.

When is independent surgery appropriate?

After approximately 500 operations for complicated cataract, I no longer treat a colleague’s presence as mandatory for every complex case. Such independence is appropriate only when the surgeon can perform a sound anterior vitrectomy, stabilise the eye and has vitreoretinal capability—or immediate access to it.

What do I check after surgery?

Slit-lamp examination covers the cornea, anterior chamber depth and reaction, iris and IOL position, anterior vitreous and inflammation. If media opacity prevents posterior segment assessment, I use B-scan ultrasonography; UBM is reserved for questions about IOL/haptic position or the ciliary sulcus. With a favourable course, my baseline review schedule is days 1, 3, 7 and 30, with earlier or additional assessment whenever risk warrants it.

Matvey Y. Shemyakin, MD · ophthalmic surgeon

Why can postoperative treatment not be identical for every case?

After complex surgery, not only the drops but the purpose of follow-up changes. A universal regimen creates false standardisation where different mechanisms require surveillance.

ScenarioPrimary objectiveWhat changes
Uncomplicated surgeryControl inflammation and prevent infectionRoutine topical regimen and follow-up; NICE advises against mandatory day-one review specifically after uncomplicated surgery.
Diabetes / DRDetect macular oedemaMacular OCT according to baseline disease and symptoms; treatment is individualised.
UveitisAvoid inflammatory reactivationOperate preferably in a quiet phase; perioperative intensity and taper reflect disease activity.
GlaucomaDetect early IOP riseEarly IOP measurement and caution with steroid response.
PCR / anterior vitrectomyMonitor inflammation, IOP, macula, retina and IOLCloser surveillance, peripheral retinal assessment, OCT and ultrasonography according to the clinical picture.
Endothelial dysfunctionPreserve corneal clarityMonitor oedema and thickness; discuss endothelial keratoplasty if recovery does not occur.

ESCRS recommends customising follow-up to ocular comorbidity [ESCRS]. The day 1–3–7–30 schedule is my protocol for complex procedures, not a universal international standard.

What is well supported, and where does uncertainty remain?

Preoperative risk stratification

Large registries consistently associate PCR with pseudoexfoliation/phacodonesis, mature cataract, small pupil and glaucoma.

High confidence

Experience and supervision

Crude rates are higher for early trainees, but results depend on case selection, training structure and senior support.

Moderate confidence

Tailored postoperative care

Guidelines support changing surveillance for diabetes, uveitis, glaucoma and complications, although regimens vary.

Moderate confidence

A specific IOL for rescue fixation

Selection depends on anatomy and technique; comparative evidence for individual specialised designs remains limited.

Limited confidence

Open questions

  • Do we need one international grading system for surgical complexity?
  • When does prophylactic CTR implantation offer more benefit than added manipulation?
  • Where is the boundary between complex-case training and patient safety?
  • How should prognosis be standardised when the fundus cannot be visualised?

References

МШ
Matvey Y. Shemyakin, MD

Ophthalmologist and ophthalmic surgeon, Moscow City Ophthalmology Centre, Botkin Hospital; junior research fellow. Clinical interests include complex cataract surgery, IOL dislocation, glaucoma and corneal disease.

Published and reviewed: 30 September 2026

For healthcare professionals. This educational material does not replace clinical guidelines, device instructions for use or the operating surgeon’s judgement in an individual case.

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